The Buffalo Bills will play their first game at Highmark Stadium under the lights of prime time.
They'll host the Detroit Lions on Thursday Night Football in Week 2 for their home opener.
Lights. Camera. (TNF) Action. 🤩
— Buffalo Bills (@BuffaloBills) May 11, 2026
📺 NFL Schedule Release 5/14 at 8pm ET on@nflnetwork pic.twitter.com/R99KYAjjmX
The matchup will mark the first meeting between the two teams since they combined for 90 points in a 48-42 victory for Buffalo in Week 15 of the 2024 season.
The Bills have won their last four home openers. They also played a prime-time game for their home opener last year, beating the Baltimore Ravens 41-40 on Sunday Night Football in Week 1.
The NFL will reveal the full 2026 schedule on Thursday at 8 p.m. ET.
